MSDS for 1-Bromo-2-Chloroethane

Identification

Product Name: 1-Bromo-2-Chloroethane
Chemical Formula: C2H4BrCl
CAS Number: 107-04-0
Synonyms: Ethane, 1-bromo-2-chloro-; Ethylene Bromochloride
Recommended Use: Laboratory uses, solvent, intermediate in organic synthesis
Supplier Information: Manufacturer and distributor contact details must be confirmed before handling
Emergency Phone: Local poison control or supplier emergency line

Hazard Identification

GHS Classification: Acute Toxicity (oral, inhalation, dermal); Skin and eye irritant
Signal Word: Danger
Hazard Statements: Toxic if inhaled, swallowed, or absorbed through skin; causes severe eye and skin irritation
Pictograms: Skull and crossbones, exclamation mark
Precautionary Statements: Avoid all contact with skin, eyes, and clothing; do not breathe vapor; wear appropriate protective gear
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Effects: Respiratory tract irritation, central nervous system depression, nausea, headache, possible unconsciousness
Chronic Effects: Prolonged or repeated exposure can cause organ damage, especially to liver and kidneys
Environmental Hazards: Harmful to aquatic life with long-lasting effects

Composition / Information on Ingredients

Chemical Name: 1-Bromo-2-Chloroethane
CAS Number: 107-04-0
Concentration: ≥ 98%
Impurities: Trace organic halides, water (≤ 1%)
Other Components: None significant in commercial-grade material
Stabilizers: None added unless specified by supplier

First Aid Measures

Inhalation: Move person to fresh air immediately, keep at rest, monitor breathing, seek medical attention if symptoms develop
Skin Contact: Rinse exposed skin with copious amounts of water, remove contaminated clothing, seek urgent medical advice for irritation
Eye Contact: Rinse cautiously with water for at least 15 minutes, hold eyelids open, obtain medical attention without delay
Ingestion: Rinse mouth, do not induce vomiting, never give liquids to an unconscious person, give nothing by mouth if convulsions or unconsciousness present, consult a physician
Most important symptoms and effects: Breathing problems, drowsiness, skin or eye burns, neurological symptoms
Immediate Medical Attention: Necessary for all severe exposures or if unconsciousness, breathing difficulty or persistent irritation occurs

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, water spray (avoid direct stream on burning liquid)
Unsuitable Extinguishing Media: Water jet may spread the fire
Hazardous Combustion Products: Hydrogen chloride, hydrogen bromide, phosgene, carbon oxides
Fire Hazards: Vapors may form explosive mixtures with air, heavier-than-air vapors may travel to distant ignition source, flashback possible
Special Firefighting Procedures: Use self-contained breathing apparatus and full protective gear, stay upwind, remove containers from fire area if safe
Explosion Data: May produce toxic or corrosive gases on heating or combustion
Additional Precautions: Cool exposed containers with water fog, prevent fire-fighting runoff from entering water sources or sewer

Accidental Release Measures

Personal Precautions: Evacuate area, ensure adequate ventilation, avoid breathing vapor, wear chemical-resistant gloves and safety goggles
Protective Equipment: Chemical splash goggles, gloves, respirator approved for toxic organic vapors, impervious clothing
Environmental Precautions: Prevent entry to sewers, soil, or waterways, contain spill with inert absorbent
Spill Cleanup Methods: Absorb in vermiculite, sand, or inert material, collect in chemical waste container, ventilate area
Decontamination: Wash spill site after material pickup
Large Spill Response: Evacuate non-essential personnel, dike area, contact emergency services, consult environmental authorities
Disposal: Dispose according to local, regional, national, and international regulations

Handling and Storage

Handling: Use only in a well-ventilated area, avoid all contact with skin and eyes, use fume hood for laboratory work, do not breathe vapor or mist
Safe Practices: Keep away from heat, open flames, sources of ignition, use spark-proof tools and explosion-proof equipment, keep containers tightly closed
Storage Conditions: Store in cool, dry, well-ventilated area, away from direct sunlight, incompatible materials, oxidizing agents, acids, bases
Container Requirements: Use only approved containers for halogenated solvents, keep tightly sealed when not in use
Incompatibilities: Strong bases, strong acids, oxidizers, alkali metals, finely divided metals
Special Storage Concerns: Label storage area for toxic chemicals, store away from food and feedstuffs

Exposure Controls and Personal Protection

Occupational Exposure Limits: Consult current ACGIH, OSHA, or local authority guidelines, no established OEL for this substance; recommend minimizing exposure as much as possible
Engineering Controls: Laboratory fume hood, mechanical general and local exhaust ventilation, explosion-proof electrical fixtures
Eye/Face Protection: Chemical splash goggles, face shield for higher risk work
Skin Protection: Chemically resistant gloves (e.g. butyl rubber, nitrile), lab coat, protective sleeves
Respiratory Protection: NIOSH/MSHA-approved full-face respirator with organic vapor cartridge for high concentrations or emergency situations
Contamination Control: Remove contaminated clothing, wash hands and face thoroughly after handling, do not eat, drink or smoke during use
Environmental Exposure: Prevent chemical from escaping into environment, employ closed system transfers if possible

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Sweet, mildly irritating
Odor Threshold: Not determined
Melting Point/Freezing Point: Approximately -67°C
Boiling Point: About 108–109°C
Flash Point: 34°C (closed cup)
Evaporation Rate: Not determined
Flammability: Combustible liquid
Upper/Lower Flammability or Explosive Limits: Information not available
Vapor Pressure: ~27 mmHg at 25°C
Vapor Density: Heavier than air
Relative Density: Approximately 1.66 (water = 1)
Solubility: Slightly soluble in water, miscible with most organic solvents
Partition Coefficient (n-octanol/water): Not established
Auto-ignition Temperature: Not available
Decomposition Temperature: Not available
Viscosity: Not determined

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage
Hazardous Reactions: Risk of violent reaction with strong bases, strong oxidizers, alkali metals
Conditions to Avoid: Elevated temperatures, ignition sources, incompatible materials
Incompatible Materials: Avoid contact with alkali metals, strong acids and bases, reducing agents, finely divided metals
Hazardous Decomposition Products: Hydrogen halides (HCl, HBr), phosgene, carbon monoxide, carbon dioxide
Polymerization: Not expected under standard conditions

Toxicological Information

Acute Toxicity (Oral, Dermal, Inhalation): Harmful to fatal; LD50 (oral, rat): 430 mg/kg; LC50 (rat, inhalation): 9 mg/L/4h (approximate values)
Skin Corrosion/Irritation: Causes moderate to severe irritation on contact
Eye Damage/Irritation: May cause permanent injury
Respiratory Effects: Cough, breathing difficulty, pulmonary edema in high dose exposures
Sensitization: Not classified, but caution warranted
Chronic Toxicity: May damage liver, kidneys, and central nervous system with prolonged or repeated exposure
Carcinogenicity: Not classified by IARC or NTP
Reproductive Toxicity: No conclusive evidence; out of caution, minimize exposure
Other Data: May cause drowsiness or dizziness, direct solvent action on skin can cause dermatitis
Symptoms of Overexposure: Dizziness, nausea, respiratory distress, unconsciousness, convulsions at very high exposures

Ecological Information

Ecotoxicity: Toxic to aquatic organisms, may cause long-term effects in aquatic environments
Persistence and Degradability: Not readily biodegradable, persists in environment
Bioaccumulation Potential: Moderately bioaccumulative, potential to concentrate in organisms
Mobility in Soil: Low to moderate mobility; has potential for groundwater contamination
Other Adverse Effects: Evaporates into the atmosphere, contributes to photochemical smog, may be persistent in nature

Disposal Considerations

Waste Methods: Dispose via approved hazardous waste incineration facility, chemical destruction under expert supervision, avoid discharge to environment
Container Disposal: Triple rinse, puncture or crush prior to landfill disposal, or handle as hazardous waste if contaminated
Special Instructions: All local, state, regional, and national laws governing disposal of hazardous chemicals must be followed
Additional Precautions: Do not attempt neutralization or open burning without specialist advice, trace residue should be managed with full PPE
Recycling Information: Not practical due to toxicity and complexity; do not reuse containers

Transport Information

UN Number: UN 2664
UN Proper Shipping Name: Bromo-chloroethanes
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: II
Labels Required: Toxic, Environmental Hazard
Marine Pollutant: Yes
Special Precautions: Protect container from mechanical damage, segregate from incompatible materials in transport
Transport in Bulk (Annex II of MARPOL 73/78 and IBC Code): Subject to regulations for toxic liquid substances

Regulatory Information

TSCA: Listed on the United States Toxic Substances Control Act inventory
OSHA: Subject to regulation as a toxic and hazardous substance
SARA Title III: May be subject to reporting; check Section 302/304/313 lists
EU Classification: Xn (Harmful), T (Toxic), N (Dangerous for the Environment) according to Regulation (EC) No 1272/2008 (CLP)
REACH Status: Registration and authorization may be required within the European Union
WHMIS (Canada): Classified as D1B (Toxic by inhalation), D2B (Skin/Eye Irritant)
Other Regulations: Check all applicable national and international requirements before use or disposal, maintain safety data for all users