MSDS for 1-Bromo-2-Methylpropane

Identification

Product Name: 1-Bromo-2-Methylpropane
Synonyms: Isobutyl bromide, 2-Methyl-1-bromopropane
CAS Number: 78-77-3
Recommended Use: Laboratory chemicals, chemical synthesis
Supplier: Chemical manufacturer or distributor
Contact Information: Supplier phone number and address
Emergency Phone Number: CHEMTREC or local poison control

Hazard Identification

GHS Classification: Flammable liquid (Category 3), Acute toxicity (inhalation, Category 4), Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity (single exposure, Category 3)
GHS Label Elements: Signal word – Warning, Hazard pictograms – Flame, Exclamation mark
Hazard Statements: Flammable liquid and vapor, Harmful if inhaled, Causes skin and eye irritation, May cause drowsiness or dizziness
Precautionary Statements: Keep away from sparks and open flames, Avoid breathing vapor, Wash thoroughly after handling, Use only outdoors or in well-ventilated area
Routes of Exposure: Inhalation, skin and eye contact, ingestion

Composition / Information on Ingredients

Chemical Name: 1-Bromo-2-Methylpropane
Common Name: Isobutyl bromide
CAS Number: 78-77-3
Concentration: >99%

First Aid Measures

Inhalation: Move person to fresh air, keep at rest in position comfortable for breathing, seek medical attention if breathing gets difficult or symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for at least 15 minutes, seek medical care if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical care
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical attention, never give anything by mouth to an unconscious person
Most Important Symptoms: Respiratory tract irritation, skin and eye irritation, dizziness, headache, nausea

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray used in small quantities
Unsuitable Extinguishing Media: Direct water jet may spread fire
Fire Hazards: Vapors are heavier than air and may travel to ignition source, forms explosive mixtures with air
Hazardous Combustion Products: Hydrogen bromide gas, carbon monoxide, carbon dioxide
Firefighter Protection: Self-contained breathing apparatus (SCBA), full protective gear against fumes and toxic gases

Accidental Release Measures

Personal Precautions: Evacuate unprotected personnel, ventilate area, wear appropriate protective equipment including gloves and goggles
Environmental Precautions: Prevent spills from entering drains, waterways, or soil
Containment and Cleanup: Absorb with non-combustible material such as sand or vermiculite, place in chemical waste container, wash spill area with soap and water, ventilate area after cleanup, eliminate all ignition sources

Handling and Storage

Handling: Avoid inhalation, ingestion, and contact with skin and eyes, use only in fume hood or well-ventilated place, ground and bond containers during transfer, keep away from sources of ignition
Storage: Store in tightly closed original containers, cool, dry, well-ventilated area designed for flammable and toxic chemicals, separate from incompatible substances such as strong oxidizers, acids, bases, and sources of heat, use corrosion-resistant shelving

Exposure Controls and Personal Protection

Engineering Controls: Use chemical fume hood, local exhaust ventilation to minimize vapor concentrations
Respiratory Protection: NIOSH/MSHA approved respirator where vapors exceed exposure limits, use supplied-air respirator in case of insufficient ventilation
Skin Protection: Chemical-resistant gloves (nitrile, neoprene), long-sleeved lab coat or clothing
Eye/Face Protection: Chemical safety goggles or face shield
Occupational Exposure Limits: No specific OSHA or ACGIH limits established, minimize exposure following general laboratory hygiene practices

Physical and Chemical Properties

Appearance: Colorless liquid
Odor: Sweet, ether-like
Odor Threshold: Not available
pH: Not applicable
Melting Point: -119°C
Boiling Point: 91–93°C
Flash Point: 24°C (closed cup)
Flammability: Flammable
Vapor Pressure: 52 mmHg at 25°C
Vapor Density: 4.5 (air = 1)
Relative Density: 1.173 g/mL at 25°C
Solubility: Insoluble in water, soluble in organic solvents (alcohol, ether, chloroform)
Partition Coefficient: log Kow 2.6
Autoignition Temperature: 430°C
Decomposition Temperature: Not available
Viscosity: Not available

Stability and Reactivity

Chemical Stability: Stable in closed containers at room temperature under recommended conditions
Reactivity: May react vigorously with oxidizing agents, strong acids or alkalis
Hazardous Reactions: May form toxic hydrogen bromide gas on thermal decomposition
Conditions to Avoid: Heat, sparks, open flames, electrostatic discharge, incompatible substances
Incompatible Materials: Oxidizing agents, strong acids, bases, aluminum, magnesium
Hazardous Decomposition Products: Hydrogen bromide, carbon oxides

Toxicological Information

Routes of Exposure: Eyes, skin, inhalation, ingestion
Acute Toxicity: Inhalation causes respiratory tract irritation, CNS effects, possible drowsiness and dizziness; oral exposure may lead to GI irritation and symptoms;
Skin Corrosion/Irritation: Causes irritation, may be absorbed through skin
Serious Eye Damage/Irritation: Causes eye irritation, redness, watering, pain
Respiratory/Skin Sensitization: Not a known sensitizer
Germ Cell Mutagenicity: No data available
Carcinogenicity: Not identified as carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No data available
STOT-single Exposure: May cause respiratory and central nervous system depression
STOT-repeated Exposure: No reliable data
Aspiration Hazard: No data
Delayed/Immediate Effects: Dizziness, nausea, headache, coughing expected at high concentrations

Ecological Information

Ecotoxicity: Toxic for aquatic organisms, may cause long-term adverse effects in aquatic environment
Persistence and Degradability: Not expected to be readily biodegradable
Bioaccumulative Potential: Potential for bioaccumulation exists, moderate log Kow
Mobility in Soil: Low mobility, volatilizes from soil or water
Other Adverse Effects: Avoid release to environment, environmental hazard not fully studied

Disposal Considerations

Waste Disposal Methods: Dispose of as hazardous chemical waste according to federal, state, and local regulations; do not flush down the drain; consult environmental agency for proper chemical incineration or disposal facility
Contaminated Packaging: Rinse container, destroy and dispose in accordance with local legislation
Special Precautions: Handle residue and spill cleanup materials as hazardous waste

Transport Information

UN Number: UN2344
UN Proper Shipping Name: 1-Bromo-2-Methylpropane
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Label: Flammable Liquid
Marine Pollutant: Yes
Special Transport Precautions: Keep container tightly closed and upright, avoid rough handling, keep away from heat sources, comply with all transportation regulations

Regulatory Information

TSCA (USA): Listed
SARA Title III (Sections 311/312): Immediate (acute) health hazard, fire hazard
SARA 313: Not subject to reporting
California Prop 65: Not listed as carcinogen or reproductive toxin
WHMIS (Canada): B2 Flammable Liquid, D2B Toxic Material
DSL/NDSL (Canada): Listed
REACH (EU): Registered, subject to regulation
Other Regulations: Users must check for regional or local restrictions, report significant spills to authorities as required